> 技术资料 > 医药原料 > 伊布莫仑甲磺酸盐【MK677_Tbutamoren】【159752-10-0】

伊布莫仑甲磺酸盐【MK677_Tbutamoren】【159752-10-0】

中文名称:伊布莫仑甲磺酸盐
英文名称:2-amino-2-methyl-N-[(2R)-1-(1-methylsulfonylspiro[2H-indole-3,4'-piperidine]-1'-yl)-1-oxo-3-phenylmethoxypropan-2-yl]propanamide, methanesulfonic acid
英文别名:Ibutamoren mesilate; Ibutamoren (Mesylate); MK-677; Ibutamoren mesylate (USAN); MK-0677;

MK-677(l-163191)是一种化合物,它作为一个强有力的,有效的促生长激素分泌,模仿GH刺激内源性激素的作用。
它已被证实能增加的释放,并产生持续增加等离子体水平的一些激素包括GH和胰岛素样生长因子1(igf - 1),但不影响皮质醇水平。
目前正在开发的潜在治疗减少了这些激素的水平,比如在儿童或老年人与生长激素缺乏症,和人类研究显示增加肌肉和骨矿物质密度,使之成为一个有前途治疗虚弱的老人。它也改变体内脂肪的代谢,所以可能在肥胖的治疗中的应用。
MK-677参考资料:
一些MK-677研究显示MK-677剂量是25mgs-50mgs当它是口头的。换句话说,25mgs-50mgs是分子口服剂量。MK 677已被证明增加释放,并产生持续的血浆中多种激素包括生长激素和IGF-1水平的增加,但不影响皮质醇水平。伊布莫仑(MK 0677、MK 677,L 163191)是由默克公司开发和研制了一种口服活性生长激素分泌剂。这是一种螺哌啶化合物。它可以模拟生长激素释放肽活性。

MK 677,也被称为Nutrabol和Ibutamoren,是当今互联网上*受欢迎的产品之一。这在公众眼中已经有一段时间了。这有时被称为“神奇药物”或“生命之泉”。但真正让我印象深刻的是,这款产品不仅*适合健身,而且有可能治疗老年痴呆症。然而,在尝试这个产品之前,我对它做了一些研究。别人可能已经说服我关于这个产品的功效,但它仍然支付如果你亲自了解更多关于药物,检查任何反馈关于其副作用,用户可以得到的好处,以及其他附加信息.

MK677和后循环疗法

MK 677是一种非常**的产品,特别是对于膨胀周期。这就是为什么在服用了MK 677之后,我还在怀疑这个产品是否需要一个后周期治疗或PCT。但由于该产品不会抑制自然睾酮的产生,也不会影响自然生长激素的产生,这就意味着没有必要进行周期后治疗。当我们使用像MK 677这样的产品时,我们应该*先意识到这种药物是如何影响我们的身体的,然后再进行测试。它可能是一种安全的产品,但滥用或滥用它会导致我们意想不到的负面结果。如果我们对我们摄入的所有东西都很了解,以确保它是安全**的,这仍然是*好的。

MK677属于Sarms系列产品中的一种与其他大多数SARMs一样,MK677(Nutrobal)通过定位特定的雄激素受体来改变它们在体内的功能。其结果是,这种刺激方式可以模仿类固醇和前激素的合成代谢作用。MK 677 (Nutrobal)与Ipamorelin和GHRP-6之类的肽非常相似,但是您不会体验到任何典型的副作用。这就是为什么像MK 677这样的SARMS在健身和医药科学*域被认为是游戏改变者。此外,MK 677 (Nutrobal)在提高生长激素脉搏强度方面的积极作用如下:

1,抑制生长抑素受体的信号。

2,减慢系统中somastostatin的活性。

3,提高生长激素释放激素(GHRH)的生长激素信号放大和增加GHRH的整体生产和释放。

除了IGF-1和生长激素水平的急剧变化之外,在MK 677上,还可以从循环中获得很多好处,包括:

1,韧带、肌腱、骨骼以及旧伤的快速愈合

2,建立精瘦的肌肉和尺寸增加增加脂肪的氧化

3,在减肥后还被证明能放松紧绷的皮肤.

MK 677用户表示,在使用GHS时,他们在短短几天的时间内就注意到自己的整体体型出现了积极的变化。除了肌肉看起来比以前更丰满,血管化,他们能够获得的收获也更**。

我认为MK 677是一种SARM,你应该根据四个关键因素来使用它:易用性,**性,*小的副作用和临床证明的结果。由于它能提高HGH水平,就好像你在服用HGH一样。如果你还在专注于SARM,那么Nutrobal*对是一个你应该考虑的选择。

CAS号:159752-10-0
含量:99% HPLC
外观:白色晶体粉末
分子式:C28H40N4O8S2
分子量:624.76900
精确质量:624.22900
PSA:196.66000
LogP:4.97440
沸点:868.9ºC at 760 mmHg
闪点:479.3ºC
蒸汽压:3.05E-32mmHg at 25°C

MK 677 (Nutrobal)
Product name: MK-677
Other name: Ibutamoren mesylate, Nutrobal, Ibutamoren, Oratrope, Crescendo
CAS No: 159752-10-0
Molecular Weight: 624.7692
Purity: 99% HPLC

Produced by Reverse Pharmacology, MK 677 (commonly known as Nutrobal or Ibutamoren) is an orally administered growth hormone secretagogue that is designed to stimulate the pituitary gland to release growth hormone. Yes, that’s right – this stuff is able to boost your growth hormone levels. It was originally formulated to manage health problems like osteoporosis, obesity and muscle wasting, but MK 677 has been shown to promote an increase in lean body mass as well as a boost in IGF-1 serum concentration during clinical runs.

How MK 677 (Nutrobal) Works?
Like most other SARMs, Nutrobal works by targeting specific androgen receptors and alters the way they function in the body.
This is why SARMS like MK 677 are considered as game changers in the world of fitness and in pharmaceutical science.

Moreover, here are the positive effects of MK 677 (Nutrobal) in terms of improving growth hormone pulse intensity:
Inhibits the signalling of somatostatin receptors;
Slows down the activity of somatostatin in the system;
Improves somatotroph signalling in growth hormone releasing hormones (GHRH);
Amplifies and increases the overall production and release of GHRH.

Benefits of MK 677 (Nutrobal):
a more rapid healing of ligaments, tendons, bones as well as old injuries
builds lean muscle mass and size gains
increases the oxidation of fat
and has even been shown to loosen tight skin after weight loss

In Terms of Sleep:
Most users who have already tried taking MK 677 shared that they experienced better sleep while on this growth hormone secretagogue. They also had an increase in vivid dreaming in the process, which made going to bed much more satisfying and exciting from their perspective.

In Terms of Skin Improvement:
A number of users relate that they experienced an improvement in their skin when they integrated MK 677 in their bodybuilding program. Here are just a few of the positive feedback that they shared:

In Terms of Achieving Gains and Shredding:
MK 677 users relate that they noticed positive changes in their overall physique in just a few days’ time while using this GHS. Apart from having their muscles looking fuller and vascular than before, the gains they are able to achieve are much more distinct as well.

MK 677 Results
If you want to know what to expect from MK 677, let me give you some information. I personally have used MK 677 and let me tell you, it is good stuff. The MK 677 Results are so amazing because of the fact that it not only improves your HGH levels, but it can also improve sleep/appetite.

The MK 677 results might take a while to see, as it is advised to run the compound for longer periods of time. The users in the below images said they ran the compound for up to a minimum of 3 months. The dosage was anywhere from to 10 to 30mgs, as that is said to be the sweet spot for the best MK 677 results.

• Bulking:
MK677 does wonders when it comes to muscle growth and new muscle cells development. There are hardly any stimulants present in the market that help you bulk up without water retention and fat gain. But this compound does not involve any such side effects and is, therefore, one of the best options you should go for during your bulking phase. This compound should definitely be added to your diet. It does not only develop your existing muscle cells but also adds new muscle cells. Also, it considerably improves your recovery time and thus helps you with weight lifting.

• Shredding:
This is a benefit that most of the people don’t know about. This hunger hormone helps you shred your fat real quick. You can add this hormone in your diet along with other hormones to stave off your cravings. This compound will help you gain hard muscles without any risk of fat gain or water retention.

Recommended MK677 Dosage
Studies have already been done on dosing the of MK 677 ranging from 10mg all the way to 50mg.
What they found is that while the HGH levels were NO HIGHER than at 50mg than those who took 10mg, it DID show an increase in IGF levels.
As a general guideline, most users suggest a sweet spot of about 25mg per day, which could increase IGF levels by as much as 80% during the first 30 days at 25mg.

Tip: Take it right before bed for maximum effect and some extra dreaming benefits.

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